In Vivo Mononuclear Cell Tracking Using Superparamagnetic Particles of Iron Oxide.

The article presents a study which aimed to develop a safe method of labeling competent peripheral blood mononuclear cells using superparamagnetic particles of iron oxide (SPIO) and to evaluate its potential for magnetic resonance cell tracking in humans. The researchers used a phased-dosing study. They found that human peripheral mononuclear cells can be labeled with SPIO without affecting their efficacy and safe for magnetic resonance cell tracking.