Microfluidic systems with free definable sensor spots by an integrated light-addressable potentiometric sensor.

Abstract: The integration of sensors in microfluidic systems is of special interest to build up lab-on-chip devices or micro-total-analysis-systems (μTAS). Those systems allow quick and cost-effective analysis with a minimum need of sample volumes. One drawback of present systems is the rigid sensor layout which has to be defined early during the design and the manufacturing of a new lab-on-chip system. This work will present the utilization of a light-addressable potentiometric sensor (LAPS) in combination with a microfluidic set-up, for the flexible adjustment of the size, the shape and the location of sensor spots at operation time. [Copyright &y& Elsevier]