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Anti-oxidant effect of picroside II in a rat model of cerebral ischemia/reperfusion injury.

Authors :
Li Sun
Xiaodan Li
Ling Wang
Lihua Qin
Yunliang Guo
Zhen Zhou
Source :
Neural Regeneration Research; May2011, Vol. 6 Issue 15, p1141-1146, 6p
Publication Year :
2011

Abstract

The article presents an in vivo study regarding the anti-oxidant effect of picroside II, an active component extracted from the rhizome and roots of Picrorhiza kurroa, in rats with cerebral ischemia/reperfusion injuries. The study used enzyme-linked immunosorbent assay and immunohistochemistry. Results showed that picroside II exhibited a neuroprotective effect by inhibiting neuronal apoptosis and downregulating inducible nitric oxide synthase expression.

Details

Language :
English
ISSN :
16735374
Volume :
6
Issue :
15
Database :
Supplemental Index
Journal :
Neural Regeneration Research
Publication Type :
Academic Journal
Accession number :
67473388
Full Text :
https://doi.org/10.3969/j.issn.1673-5374.2011.15.004