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iNKTs Foil Fungi.

Authors :
Prlic, Martin
Hohl, Tobias M.
Source :
Cell Host & Microbe; Nov2011, Vol. 10 Issue 5, p421-422, 2p
Publication Year :
2011

Abstract

Fungal cell wall polysaccharides are potent inducers of immune responses. demonstrate that innate recognition of fungal β-(1,3) glucan triggers effector functions of invariant natural killer T (iNKT) cells through indirect, cytokine-driven activation, a process that mediates optimal protection against the opportunistic mold Aspergillus fumigatus. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
19313128
Volume :
10
Issue :
5
Database :
Supplemental Index
Journal :
Cell Host & Microbe
Publication Type :
Academic Journal
Accession number :
67327155
Full Text :
https://doi.org/10.1016/j.chom.2011.11.003