Comparative Lipidomics Profiling of Human Atherosclerotic Plaques.

The article discusses a study on the latest mass spectrometry (MS) developments in shotgun lipidomics which compared radial arteries, endarterectomy samples from symptomatic and asymptomatic patients and stable and unstable areas within the same symptomatic lesion. Twenty six patients were included in the study and the control radial arteries were carefully chosen. It refers to the study as the most comprehensive MS analysis of the lipid content in human atherosclerotic plaques to date.