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Identification and Evolution of Venom Phospholipase A2 Inhibitors from Protobot/irops elegans Serum.

Authors :
Shuhei So
Murakami, Tatsuo
Naoki Ikeda
Takahito Chijiwa
Oda-Ueda, Naoko
Kuraishi, Takeshi
Hattori, Shosaku
Ohno, Motonori
Source :
Bioscience, Biotechnology & Biochemistry; Mar2011, Vol. 75 Issue 3, p480-488, 9p
Publication Year :
2011

Abstract

The article presents a study on the identification and evolution of venom phospholipase A2 (PLA2) inhibitors (PLIs) from Protobothrops elegans serum. P. elegans snakes were used as the study samples. The study utilizes several methods including mass spectrometry (MS), far-western blotting analysis and purification of the PLIs from the P. elegans serum. It also revealed the isolation of PeyPLI-A and PeyPLI-B cDNAs from the P. elegans liver cDNA library and their nucleotide sequences.

Details

Language :
English
ISSN :
09168451
Volume :
75
Issue :
3
Database :
Supplemental Index
Journal :
Bioscience, Biotechnology & Biochemistry
Publication Type :
Academic Journal
Accession number :
62542992
Full Text :
https://doi.org/10.1271/bbb.100676