Paraffin-embedded tissue blot as a sensitive method for discrimination between classical scrapie and experimental bovine spongiform encephalopathy in sheep.

Authors :: Webb, Paul R.
Denyer, Margaret
Gough, Julie
Spiropoulos, John
Simmons, Marion M.
Spencer, Yvonne I.
Source :: Journal of Veterinary Diagnostic Investigation; May2011, Vol. 23 Issue 3, p492-498, 7p, 4 Black and White Photographs, 1 Chart
Publication Year :: 2011
Abstract: The article describes the modification of the paraffin-embedded tissue (PET) blot for use as a tool to differentiate between classical scrapie and experimental bovine spongiform encephalopathy (BSE) in sheep. The method was developed by using medulla (obex) from 21 cases of classical scrapie and 6 cases of experimental ovine BSE. The success of the differential PET blot in differentiating between all of the scrapie and ovine BSE cases is also discussed.

Subjects :: ALKANES
SCRAPIE
BOVINE spongiform encephalopathy
VIRUS diseases in sheep
MEDULLA oblongata

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