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Hereditary angio-oedema: Long-term prophylaxis with danazol.
- Source :
- Respiratory Medicine CME; Mar2011, Vol. 4 Issue 1, p15-16, 2p
- Publication Year :
- 2011
-
Abstract
- Abstract: Hereditary angio-oedema is a rare autosomal dominant disease characterized by recurrent attacks of subcutaneous oedema and caused by a deficiency of the plasma protein C1 inhibitor. Hereditary angio-oedema attacks carry a high risk of morbidity or even mortality. In literature, there are only a few publications on the treatment and follow-up of paediatric patients. We report the case of a 14-year-old male with known hereditary angio-oedema since the age of six years, revealed by a recurrent acute abdominal pain and oedema in subcutaneous tissues of extremities and face, and he was admitted once for sub mucosal oedema of larynx with suffocation, treated by fresh-frozen plasma with favourable outcome. Danazol was used for long-term prophylaxis. Clinical course improved over a follow-up of 12 months. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 17550017
- Volume :
- 4
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Respiratory Medicine CME
- Publication Type :
- Academic Journal
- Accession number :
- 60563589
- Full Text :
- https://doi.org/10.1016/j.rmedc.2010.01.006