Plasma Leptin Concentration in Dogs with Diabetes Mellitus.

The article provides information on a study which evaluated the plasma leptin concentration in dogs with diabetes mellitus. A total of 36 dogs, normal and diabetic, were divided into non-obese and obese groups based on body condition score. Plasma leptin concentrations in obese normal dogs were significantly higher than that of the non-obese normal dogs. There was no significant difference between the plasma leptin concentrations of non-obese and obese diabetic dogs. Furthermore, the obese diabetic dogs had significantly lower plasma leptin concentration than that in the obese normal dogs. The results indicate that the plasma leptin concentrations in the diabetic dogs were influenced by factors other than adiposity.