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Successful treatment with carboplatin and etoposide in a small-cell lung cancer patient undergoing hemodialysis.
- Source :
- Respiratory Medicine CME; Feb2010, Vol. 3 Issue 2, p68-70, 3p
- Publication Year :
- 2010
-
Abstract
- Abstract: Chemotherapy for cancer patients with chronic renal failure, undergoing hemodialysis (HD), has not been well established. A 78-year-old woman with chronic renal failure due to hypertensive nephropathy, undergoing HD, was diagnosed with small-cell lung cancer (SCLC) with multiple-organ metastases. She was treated with 4 cycles of carboplatin (CBDCA) and etoposide (ETP) chemotherapy and a partial response was achieved. She remained progression-free for at least 12 months after the completion of chemotherapy. Pharmacokinetic analysis (PK) revealed that both agents were rapidly eliminated by HD; however, the remnant platinum remained longer in the plasma. Chemotherapy with CBDCA and ETP was effective and could be safely administered to a patient with SCLC undergoing HD. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17550017
- Volume :
- 3
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Respiratory Medicine CME
- Publication Type :
- Academic Journal
- Accession number :
- 53390302
- Full Text :
- https://doi.org/10.1016/j.rmedc.2009.05.006