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Treatment of actinic cheilitis with imiquimod 5% and a retractor on the lower lip: clinical and histological outcomes in 5 patients.
- Source :
- British Journal of Oral & Maxillofacial Surgery; Sep2010, Vol. 48 Issue 6, p473-476, 4p
- Publication Year :
- 2010
-
Abstract
- Abstract: Imiquimod 5% (Aldara™, 3M Healthcare Ltd.) is a topically applied immune response modifier used in the treatment of superficial basal cell carcinoma, actinic keratosis, and genital warts. We reviewed the casenotes of 5 patients with histologically confirmed dysplastic lower lips who had been treated with topical imiquimod. Each patient was provided with a specially designed lower lip retractor to prevent spread of the cream. Treatment was stopped after 6 weeks or if an acute inflammatory reaction developed. The lower lip was biopsied 4 weeks later, and histologically the dysplastic changes had been reversed in all 5 patients. The lip retractor was well-tolerated, and prevented spread of the cream. Imiquimod 5% cream offers an alternative method to manage dysplastic lips. Our lip retractor is a simple and cost-effective method of isolating the lower lip and allowing application of topical agents. The method could equally well be used for agents other than imiquimod. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02664356
- Volume :
- 48
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- British Journal of Oral & Maxillofacial Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 53310653
- Full Text :
- https://doi.org/10.1016/j.bjoms.2009.08.024