Novel Cataract Mouse Model Using ddY Strain: Hereditary and Histological Characteristics.

The article examines the characteristics of the novel cataract mouse model using ddY strain reared at Osaka Prefecture University in Japan. The authors mention that opacity appeared as a white pinpoint focus in the unpigmented eyes of cataract mice at 6 weeks of age. They also state that there were no gender differences in the incidence of cataracts. They note that 5-month-old cataract mice showed vacuolation of epithelial cells and disruption of lens fibers. They also reveal that the cataract mice represent a novel cataract mouse model and have been called Morioka cataract (MCT) mice.