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Severe neonatal renal failure after maternal use of angiotensin II type I receptor antagonists.
- Source :
- Medical & Surgical Pediatrics / Pediatria Medica e Chirurgica; nov/dic2008, Vol. 30 Issue 6, p306-308, 3p, 2 Black and White Photographs, 1 Chart
- Publication Year :
- 2008
-
Abstract
- The article describes the case of severe renal failure in a 36-week old baby girl whose mother had taken Olmesartan for hypertension during her last month of pregnancy. The baby died of cardio-circulatory failure 45 days after her birth with kidneys showing severe tubular dysgenesis. Also included is information on sartans as treatment for arterial hypertension and role of renin-angiotensin components in kidney development. The study concludes that exposure to sartans during the last month of pregnancy can cause congenital malformations, renal impairment, and fetal or neo-natal death.
Details
- Language :
- English
- ISSN :
- 03915387
- Volume :
- 30
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Medical & Surgical Pediatrics / Pediatria Medica e Chirurgica
- Publication Type :
- Academic Journal
- Accession number :
- 47671237