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Variation in the 4q25 Chromosomal Locus Predicts Atrial Fibrillation After Coronary Artery Bypass Graft Surgery.

Authors :
Body, Simon C.
Collard, Charles D.
Sheman, Stanton K.
Fox, Amanda A.
Liu, Kuang-Yu
Ritchie, Marylyn D.
Perry, Tjorvi E.
Muehlschlegel, Jochen D.
Aranki, Sary
Donahue, Brian S.
Pretorius, Mias
Estrada, Juan-Carlos
Ellinor, Patrick T.
Newton-Cheh, Christopher
Seidman, Christine E.
Seidman, J. G.
Herman, Daniel S.
Lichtner, Peter
Meitinger, Thomas
Pfeufer, Arne
Source :
Circulation: Cardiovascular Genetics; Oct2009, Vol. 2 Issue 5, p499-506, 8p, 1 Diagram, 4 Charts
Publication Year :
2009

Abstract

The article presents a study on the role of the 4q25 chromosomal locus in the prediction of atrial fibrillation (AF) after coronary artery bypass graft surgery. Multivariate predictors of postoperative AF were identified by genotyping 45 single-nucleotide polymorphisms (SNPs) including the 4q25 area. Results show that the genetic variations in the 4q25 chromosomal region were associated with postoperative AF after bypass graft surgery.

Subjects

Subjects :
CHROMOSOMES
CELL nuclei
CYTOTAXONOMY
ATRIAL fibrillation
ATRIAL arrhythmias
CORONARY artery bypass

Details

Language :
English
ISSN :
1942325X
Volume :
2
Issue :
5
Database :
Supplemental Index
Journal :
Circulation: Cardiovascular Genetics
Publication Type :
Academic Journal
Accession number :
45282669
Full Text :
https://doi.org/10.1161/CIRCGENETICS.109.849075
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