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Early Diet and General Cognitive Outcome at Adolescence in Children Born at or Below 30 Weeks Gestation.
- Source :
- Journal of Pediatrics; Aug2009, Vol. 155 Issue 2, p229-234, 6p
- Publication Year :
- 2009
-
Abstract
- Objective: To test the hypothesis that effects of early diet on cognition observed at age 8 years persist in adolescents born preterm at ≤ 30 weeks gestational age. Study design: A subgroup from a preterm infant cohort recruited for a randomized trial studying the effects of early dietary intervention was assessed at age 16 years. IQ scores were compared between those assigned a high-nutrient diet (n = 49) or standard-nutrient diet (n = 46) in infancy at both 8 and 16 years. Results: At age 8 years, the high-nutrient group had higher mean Verbal IQ (VIQ; P = .03), Performance IQ (P = .01), and Full-Scale IQ (P = .02) scores compared with the standard-nutrient group; the VIQ difference persisted at adolescence (P = .02). This effect was accounted for principally by a significant difference in the mean Verbal Comprehension Index score (P < .008). Conclusions: A brief period of dietary intervention after preterm birth, principally between 26 and 34 weeks of gestation, affected IQ at age 16 years. A standard-nutrient diet was associated with lower VIQ, accounted for mainly by differences in verbal comprehension, which persisted after control of social factors. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00223476
- Volume :
- 155
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Journal of Pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 43313099
- Full Text :
- https://doi.org/10.1016/j.jpeds.2009.02.030