Evaluation of Efficacy of Bruceine A, a Natural Quassinoid Compound Extracted from a Medicinal Plant, Brucea javanica, for Canine Babesiosis.

The article presents a research on the efficacy of bruciene A, a natural quassinoid compound extracted from dried fruits of Brucea javanica, in treating canine babesiosis, a tick-borne disease caused by intraerythrocytic apicomplexan parasites Babesia gibsoni and Babesia canis. Babesia gibsoni infection is diagnosed through the causation of anemia, fever, thrombocytopenia, splenomegaly, lymphadenopathy and lethargy. Results of a clinical investigation show that bruciene A is a potential treatment for canine babesiosis.