Identification of Common Variants in the SHBG Gene Affecting Sex Hormone-Binding Globulin Levels and Breast Cancer Risk in Postmenopausal Women.

The article investigates possible associations between sex hormone-binding globulin (SHBG) levels in postmenopausal women and tagging single nucleotide polymorphisms (SNP) in or around the SHBG gene. According to the authors, at least three SNPs showed associations with SHBG levels that were highly significant but relatively small in magnitude.