Locoregional Chemotherapy Including Perfusion.

Regional chemotherapy is a form of anticancer therapy which has recently made striking advances. The rationale for regional application of cytotoxic agents is to increase local efficacy on one hand and to reduce systemic side-effects on the other hand. Regional administration of anticancer drugs may be recommended, if is known and if it is relatively localized and not disseminated. Many attempts have been made to increase the response by administering high concentrations of anticancer drugs selectively to the tumor tissue. It is advantageous for anticancer treatment if the toxic effects of the cytostatics on normal tissue are minimized by administering the drugs only to the cancer tissue in such a way that the drugs do not reach the normal tissue. [ABSTRACT FROM AUTHOR]