Boron and Prostate Cancer a Model for Understanding Boron Biology.

The aim of this paper is describe how boron was identified as an anticancer agent for prostate cancer and how research using human prostate cells identified a biochemical mechanism that may explain many of the diverse effects reported for the element in plants and animals. At physiological pH, boric acid binds to NAD+, a coenzyme in metabolism and substrate for an enzyme in the NAD+ cADPR system of calcium signaling. [ABSTRACT FROM AUTHOR]