Vasculopathy After Treatment of Choroidal Melanoma.

Uveal melanomas present in adulthood, their incidence peaking at around the age of 60 years [4]. More than 90% of uveal melanomas arise in choroid, about 40% extending close to optic disk or fovea. These tumors tend to cause visual loss from retinal pigment epithelial disease, macular edema, and exudative retinal detachment (Fig. 23.1). In advanced cases, the presence of a large intraocular tumor and extensive retinal detachment can result in rubeosis, neovascular glaucoma, phthisis, and a blind and painful eye. Approximately 50% of patients develop metastatic disease, which usually involves the liver and which is usually fatal within a few months. [ABSTRACT FROM AUTHOR]