Use of Nanobarcodes® Particles in Bioassays.

Authors :: Walker, John M.
Rosenthal, Sandra J.
Wright, David W.
Freeman, R. Griffith
Raju, Paul A.
Norton, Scott M.
Walton, Ian D.
Smith, Patrick C.
He, Lin
Natan, Michael J.
Sha, Michael Y.
Penn, Sharron G.
Source :: NanoBiotechnology Protocols; 2005, p73-83, 11p
Publication Year :: 2005
Abstract: We have developed striped metal nanoparticles, Nanobarcodes® particles, which can act as encoded substrates in multiplexed assays. These particles are metallic, encodeable, machine-readable, durable, submicron-sized tags. The power of this technology is that the particles are intrinsically encoded by virtue of the difference in reflectivity of adjacent metal stripes. This chapter describes protocols for the attachment of biological molecules, and the subsequent use of the Nanobarcodes particles in bioassays. [ABSTRACT FROM AUTHOR]