Identification of Start Sites of Bi-Directional DNA Synthesis at Eukaryotic DNA Replication Origins.

DNA replication is the key process for the conservation and transmission of genetic information in all living organisms. The bi-directional DNA replication does not start randomly along the genome but rather at precise chromosomal regions, defined as origins of DNA replication where, after specific protein-DNA interactions, regulation of the process occurs. [ABSTRACT FROM AUTHOR]