Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as Potent and Orally Active Inhibitors of Lymphocyte Specific Kinase (Lck): Synthesis, SAR, and In Vivo Anti-Inflammatory Activity.

Details

Language :

English

ISSN :

00222623

Volume :

51

Issue :

6

Database :

Supplemental Index

Journal :

Journal of Medicinal Chemistry

Publication Type :

Academic Journal

Accession number :

32793320

Full Text :

https://doi.org/10.1021/jm701095m