BAGE Hypomethylation, A New Epigenetic Biomarker for Colon Cancer Detection.

Authors :: Grunau, Christoph
Brun, Marie-Elisabeth
Rivals, Isabelle
Selves, Janick
Hindermann, Winfried
Favre-Mercuret, Magali
Granier, Guillaume
De Sario, Albertina
Source :: Cancer Epidemiology, Biomarkers & Prevention; Jun2008, Vol. 17 Issue 6, p1374-1379, 6p, 1 Diagram, 1 Chart, 5 Graphs
Publication Year :: 2008
Abstract: The article discusses the result of a study concerning B melanoma antigens (BAGE), a novel epigenetic biomarker for colon cancer detection. BAGE are a family of genes and truncated genes located in the heterochromatic regions of several human chromosomes. These markers could be used in association with hypermethylation markers to develop reliable diagnostic tests.