Adventitial Mast Cells Contribute to Pathogenesis in the Progression of Abdominal Aortic Aneurysm.

The article discusses a study which examines the role of adventitial mass cells in the progression of abdominal aortic aneurysm (AAA). Histological study of AAA tissues of patients was conducted, as well as interventional animal and cell culture experiments. The number of mast cells increased in the outer media or adventitia of human AAA, reflecting a positive correlation between the cell number and the AAA diameter.