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Leukocyte Telomere Length Predicts Cancer Risk in Barrett's Esophagus.

Authors :
Risques, Rosa Ana
Vaughan, Thomas L.
Xiaohong Li
Odze, Robert D.
Blount, Patricia L.
Ayub, Kamran
Gallaher, Jasmine L.
Reid, Brian J.
Rabinovitch, Peter S.
Source :
Cancer Epidemiology, Biomarkers & Prevention; Dec2007, Vol. 16 Issue 12, p2649-2655, 7p, 3 Charts, 2 Graphs
Publication Year :
2007

Abstract

The article focuses on a study which examined the hypothesis that leukocyte telomere length might be able to predict future risk of cancer using a cohort of patients with Barrett's esophagus, who are at increased risk of esophageal adenocarcinoma. It found that shorter telomeres were associated with increased esophageal adenocarcinoma risk and the association was significant when individually or simultaneously adjusted for age, gender, nonsteroidal anti-inflammatory drug (NSAID) use, cigarette smoking, and waist-to-hip ratio.

Details

Language :
English
ISSN :
10559965
Volume :
16
Issue :
12
Database :
Supplemental Index
Journal :
Cancer Epidemiology, Biomarkers & Prevention
Publication Type :
Academic Journal
Accession number :
31163787
Full Text :
https://doi.org/10.1158/1055-9965.EPI-07-0624