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Cyclization of the Acyl Glucuronide Metabolite of a Neutral Endopeptidase Inhibitor to an Electrophilic Glutarimide:  Synthesis, Reactivity, and Mechanistic Analysis.

Authors :
Xiaoli Meng
James L. Maggs
David C. Pryde
Simon Planken
Rosalind E. Jenkins
Torren M. Peakman
Kevin Beaumont
Christopher Kohl
B. Kevin Park
Andrew V. Stachulski
Source :
Journal of Medicinal Chemistry; Nov2007, Vol. 50 Issue 24, p6165-6176, 12p
Publication Year :
2007

Details

Language :
English
ISSN :
00222623
Volume :
50
Issue :
24
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
27793820
Full Text :
https://doi.org/10.1021/jm0706766