Functional Variant of Manganese Superoxide Dismutase (SOD2 V16A) Polymorphism Is Associated with Prostate Cancer Risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Study.

The article presents a study which evaluated the association of prostate cancer with genetic polymorphisms in manganese superoxide dismutase (SOD2 V16A). The three main isoforms of SOD are cited. The study used conditional logistic regression to estimate odds ratios (OR) and 95% confidence intervals. According to the study, no significant association with prostate cancer was observed for polymorphic variants in SOD3 or SOD1.