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DE NOVO MUTATION IN A CHOROIDEREMIA CARRIER.

Authors :
Bozbeyoglu, Simge
Fishman, Gerald A.
Stone, Edwin M.
MacDonald, Ian M.
Streb, Luan M.
Source :
Retinal Cases & Brief Reports; Summer2007, Vol. 1 Issue 3, p182-184, 3p, 4 Diagrams
Publication Year :
2007

Abstract

The article reports on a de novo gene mutation in a woman which showed the clinical characteristics of choroidemia (CHM). A single base-pair sequence mutation was observed in codon 293 in exon 7 (R293X) of the CHM gene in the proband. This mutation was not present in her clinically unaffected parents.

Details

Language :
English
ISSN :
19351089
Volume :
1
Issue :
3
Database :
Supplemental Index
Journal :
Retinal Cases & Brief Reports
Publication Type :
Academic Journal
Accession number :
25947299
Full Text :
https://doi.org/10.1097/ICB.0b013e31804d1de0