Lack of Association of Transforming Growth Factor-β1 Polymorphisms and Haplotypes with Prostate Cancer Risk in the Prostate, Lung, Colorectal, and Ovarian Trial.

The article provides information on a study that investigated the role of five single-nucleotide polymorphisms in transforming growth factor Β1 (TGFB1), chosen because of potential functional significance, in relation to prostate cancer risk. It concludes that there is no evidence of association of prostate cancer with five TGFB1 genetic polymorphisms and their haplotypic combinations in Prostate, Lung, Colorectal and Ovarian (PLCO) trial.