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Axillary sentinel lymph nodes in breast cancer: a single lymphatic pathway drains the entire mammary gland.
- Source :
- European Journal of Surgical Oncology; Jun2005, Vol. 31 Issue 5, p479-484, 6p
- Publication Year :
- 2005
-
Abstract
- Abstract: Aim: To report the pattern of lymphatic mapping following intrasubdermal injections of radiocolloid and of blue dye in different sites of the breast. Methods: Prior to surgery 137 breast cancer patients underwent intrasubdermal injection of 30–50MBq <superscript>99m</superscript>Tc-colloidal albumin over the tumour site (ISI group). Ten minutes before surgery, 2ml patent blue was injected in the subareolar area (SAI group) in 117/137 patients, while 20 patients received intrasubdermal blue-dye in the quadrant opposite the tumour site (OQI group). The different injection routes were considered concordant when the hottest sLN was also blue. Results: In 134/137 patients radiocolloid drained to one or more axillary nodes, while blue nodes were found in 98/117 SAI patients and in 17/20 OQI patients. Multiple hot nodes were found in 63/134 cases and multiple blue nodes in 35/115. In patients in whom both tracers reached the axilla, the hottest node was also blue in 108/115 cases (93/98 SAI and 15/17 OQI patients). In the seven discordant cases, the hottest node was not blue, but in two cases the blue node was also radioactive. Conclusions: Superficial lymphatic drainage from the breast most frequently merges to a single axillary lymph node, irrespective of the site of tracer injection. In a few cases different injection sites identify different, often closely interconnected sLNs. [Copyright &y& Elsevier]
- Subjects :
- BREAST cancer patients
LYMPH nodes
BREAST cancer
BREAST surgery
LYMPHATICS
Subjects
Details
- Language :
- English
- ISSN :
- 07487983
- Volume :
- 31
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- European Journal of Surgical Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 23089301
- Full Text :
- https://doi.org/10.1016/j.ejso.2005.03.001