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Endograft exclusion of acute and chronic descending thoracic aortic dissections.
- Source :
- Journal of Vascular Surgery; Feb2006, Vol. 43 Issue 2, p247-258, 12p
- Publication Year :
- 2006
-
Abstract
- Objectives: To analyze the results of endograft exclusion of acute and chronic descending thoracic aortic dissections (Stanford type B) with the AneuRx (n = 5) and Talent (n = 37) thoracic devices and to compare postoperative outcomes of endograft placement acutely (<2 weeks) and for chronic interventions. Methods: Patients treated for acute or chronic thoracic aortic dissections (Stanford type B) with endografts were included in this study. All patients (n = 42) were enrolled in investigational device exemption protocols from August 1999 to March 2005. Three-dimensional computed tomography reconstructions were analyzed for quantitative volume regression of the false lumen and changes in the true lumen over time (complete >95%, partial >30%). Results: Forty-two patients, all of whom had American Society of Anesthesiologists (ASA) risk stratification ≥III and 71% with ASA ≥ IV, were treated for Stanford type B dissections (acute = 25, chronic = 17), with 42 primary and 18 secondary procedures. All proximal entry sites were identified intraoperatively by intravascular ultrasound (IVUS). The procedural stroke rate was 6.7% (4/60), with three posterior circulation strokes. Procedural mortality was 6.7% (4/60). The left subclavian artery was occluded in 11 patients (26%) with no complaints of arm ischemia, but there was an association with posterior circulation strokes (2/11) (18%). No postoperative paraplegia was observed after primary or secondary intervention. Complete thrombosis of the false lumen at the level of endograft coverage occurred in 25 (61%) of 41 patients ≤1 month and 15 (88%) of 17 patients at 12 months. Volume regression of the false lumen was 66.4% (acute) and 91.9% (chronic) at 6 months. Lack of true lumen volume (contrast) increase and increasing false lumen volume (contrast) suggests continued false lumen pressurization and the need for secondary reintervention. Thirteen patients (31%) required 18 secondary interventions for proximal endoleaks in 6, junctional leaks in 3, continued perfusion of the false lumen from distal re-entry sites in 3, and surgical conversion in 4 for retrograde dissection. Conclusions: Preliminary experience with endografts to treat acute and chronic dissections is associated with a reduced risk of paraplegia and lower mortality compared with open surgical treatment, the results of medical treatment alone, or a combination. [Copyright &y& Elsevier]
- Subjects :
- PATIENTS
CARDIOVASCULAR diseases
AORTIC dissection
TOMOGRAPHY
BLOOD coagulation
Subjects
Details
- Language :
- English
- ISSN :
- 07415214
- Volume :
- 43
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Journal of Vascular Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 22918757
- Full Text :
- https://doi.org/10.1016/j.jvs.2005.10.065