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Hemodynamic Effects of Lidocaine in the Thoracic Paravertebral Space During One-Lung Ventilation for Thoracic Surgery.
- Source :
- Journal of Cardiothoracic & Vascular Anesthesia; Oct2006, Vol. 20 Issue 5, p648-651, 4p
- Publication Year :
- 2006
-
Abstract
- Objective: There is increasing interest in the use of the thoracic paravertebral block (TPVB) in association with general anesthesia for lung-resection surgery. The aim of the study was to evaluate the hemodynamic effects of a 5-mg/kg lidocaine bolus injected in the thoracic paravertebral space during one-lung ventilation (OLV) in noncardiac patients undergoing thoracic surgery. Design: Prospective, observational study. Setting: Tertiary care university hospital. Participant: Twenty patients undergoing thoracotomy for lung resection. Interventions: In addition to standard monitoring, cardiac output, preload parameters (global diastolic volume, total intrathoracic blood volume, and systolic volume variation), and myocardial contractility (dP<subscript>max</subscript> and cardiac function index) were measured with an aortic transpulmonary thermodilution technique. Measurements and Main Results: After OLV initiation, a paravertebral lidocaine bolus of 5 mg/kg (2%) caused decreases in the dP<subscript>max</subscript> and cardiac function index that lasted up to 30 minutes. Accompanying minor reductions in heart rate and systolic blood pressure required no vasoactive drugs and were self-limiting. None of the other hemodynamic parameters studied was significantly altered. Conclusions: In noncardiac patients, TPVB is associated with good hemodynamic stability, despite a small and transient decrease in myocardial contractility that could be related to the drug’s systemic effects after its absorption. [Copyright &y& Elsevier]
- Subjects :
- PARAVERTEBRAL anesthesia
THORACIC surgery
LIDOCAINE
HEMODYNAMICS
Subjects
Details
- Language :
- English
- ISSN :
- 10530770
- Volume :
- 20
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Journal of Cardiothoracic & Vascular Anesthesia
- Publication Type :
- Academic Journal
- Accession number :
- 22607763
- Full Text :
- https://doi.org/10.1053/j.jvca.2006.02.033