Researchers from University of Pittsburgh Detail New Studies and Findings in the Area of Breast Cancer (Cancer-cell Derived S100a11 Promotes Macrophage Recruitment In Er Plus Breast Cancer).

Researchers from the University of Pittsburgh conducted a study on the interaction between cancer cells and macrophages in estrogen receptor-positive (ER+) breast tumors. They identified S100A11 as a factor that promotes macrophage recruitment and poor outcomes in ER+ tumors. The study suggests that targeting S100A11 could be a potential therapeutic strategy to modulate the macrophage-rich tumor microenvironment in breast cancer. This research provides new insights into the crosstalk between cancer cells and macrophages in ER+ breast tumors, emphasizing the role of S100A11 as a potential therapeutic target. [Extracted from the article]