Reports on Lung Cancer Findings from Lomonosov Moscow State University Provide New Insights (Divergent Contribution of Cytoplasmic Actins to Nuclear Structure of Lung Cancer Cells).

Researchers from Lomonosov Moscow State University have found that actin isoforms play a crucial role in the nuclear structure of lung cancer cells, affecting nuclear stiffness and cellular behavior. The study suggests that b-actin is involved in chromatin compaction and deactivation, while g-actin is responsible for chromatin decondensation and activation. These findings provide new insights into the mechanisms influencing cell fate during cancer progression. The research was supported by the Russian Scientific Foundation and published in the International Journal of Molecular Sciences. [Extracted from the article]