Study Data from Sun Yat-Sen University Update Understanding of miRNA-Based Therapy (Curcumol inhibits hepatocellular carcinoma proliferation through miRNA-124/STAT3 pathway: Network pharmacology and experimental validation).

A study conducted by Sun Yat-Sen University in China explored the potential of curcumol, a compound found in a traditional Chinese herb, in inhibiting the growth of hepatocellular carcinoma (HCC) through the miRNA-124/STAT3 pathway. The research identified targets of HCC and curcumol, analyzed the effects of curcumol on HCC cell growth and apoptosis, and found that curcumol downregulated STAT3 expression. The study suggests that curcumol's impact on HCC cell growth inhibition and pro-apoptosis may be linked to the miRNA-124/STAT3 pathway. [Extracted from the article]