Researchers at University of Airlangga Report New Data on Antivirals (Molecular Dynamics Study On the Effect of the N1 Neuraminidase Double Mutant G147r/h274y On Oseltamivir Sensitivity).

Researchers at the University of Airlangga in Surabaya, Indonesia, conducted a molecular dynamics study on the effect of the N1 neuraminidase double mutant G147R/H274Y on oseltamivir sensitivity. The study revealed that this mutant variant significantly reduces the interaction of oseltamivir with certain residues, potentially impacting the efficacy of the drug. The researchers hope that these findings will contribute to the development of anti-influenza drugs that can combat mutant variants. For more information, readers can refer to the original article published in RSC Advances. [Extracted from the article]