New Biology Research from University of Maryland School of Medicine Discussed (GPR68 Mediates Lung Endothelial Dysfunction Caused by Bacterial Inflammation and Tissue Acidification).

The University of Maryland School of Medicine conducted research on the role of GPR68 in mediating lung endothelial dysfunction caused by bacterial inflammation and tissue acidification. The study found that acidic pH induced endothelial inflammation and increased permeability in human pulmonary vascular endothelial cells. The results suggest that GPR68 is a critical mediator of tissue acidification-induced dysfunction and exacerbates the effects of bacterial inflammation on endothelial cells. The research was published in Cells and can be accessed for free online. [Extracted from the article]