Investigators from University of Science and Technology China Report New Data on Staphylococcus aureus (Co-transcribed Genes Sa1833-sa1832 Promote Persister Formation By Regulating the Transcription of Holin-like Gene Lrga In...).

A recent report from the University of Science and Technology China discusses the role of co-transcribed genes SA1833-SA1832 in promoting persister formation in Staphylococcus aureus. The study found that dysfunction of these genes reduces persister formation in the presence of ceftizoxime and that their expression is regulated by the LexA-RecA pathway. Additionally, disrupting SA1833-SA1832 inhibits S. aureus from infecting macrophages and impairs its ability to survive in the intracellular environment. [Extracted from the article]