Research from Liaoning Normal University in Colon Cancer Provides New Insights (The Inhibitory Effect and Mechanism of the Histidine-Rich Peptide rAj-HRP from Apostichopus japonicus on Human Colon Cancer HCT116 Cells).

Researchers from Liaoning Normal University in China conducted a study on the inhibitory effects of a histidine-rich peptide, rAj-HRP, from the sea cucumber Apostichopus japonicus on human colon cancer HCT116 cells. The peptide showed significant inhibitory effects on cell proliferation, migration, and adhesion in vitro, as well as tumor growth in vivo. The study suggests that rAj-HRP has the potential to be a novel targeted therapy for colon cancer through the EGFR and apoptosis pathways. The research was published in the journal Molecules. [Extracted from the article]