Studies from Albany Medical College Provide New Data on Biology (Hypoxia-Induced Mitochondrial ROS and Function in Pulmonary Arterial Endothelial Cells).

Researchers from Albany Medical College conducted a study on the impact of hypoxia on pulmonary artery endothelial cells (PAECs) and their production of reactive oxygen species (ROS). The study found that hypoxia increased ROS production in PAECs, leading to enhanced migration and proliferation of the cells. Nicotine, a component of cigarettes and e-cigarettes, had no effect on migration but increased proliferation, with a further increase when combined with hypoxia. The research suggests that PAECs may contribute to pulmonary hypertension through ROS signaling. [Extracted from the article]