New proteomic signature in circulating extracellular vesicles from tumor-draining vein of lung adenocarcinomas patients.

A study published in Cancer Weekly explores the proteomic signature in circulating extracellular vesicles (EVs) from the tumor-draining vein of lung adenocarcinoma patients. The research focuses on identifying noninvasive prognostic biomarkers for locally advanced non-small cell lung cancer (NSCLC) patients. The study suggests that the proteins carried by EVs from the tumor-draining vein plasma samples could serve as promising novel biomarkers for NSCLC prognosis and early recurrence prediction. The findings are based on the analysis of EVs from tumor-draining vein and peripheral vein plasma samples of NSCLC patients, as well as tumoral and non-tumoral adjacent tissues. [Extracted from the article]