New Findings in Liver Cancer Described from Beijing University of Chemical Technology (A Myc-stambpl1-toe1 Positive Feedback Loop Mediates Egfr Stability In Hepatocellular Carcinoma).

A recent study from Beijing University of Chemical Technology explores the role of STAMBPL1 in liver cancer, focusing on its impact on the stability of the epidermal growth factor receptor (EGFR). The research suggests that STAMBPL1 deficiency can attenuate liver tumorigenesis by modulating EGFR stability and RNA splicing. The findings propose STAMBPL1 as a potential therapeutic target for liver cancer treatment, highlighting a positive feedback loop involving the EGFR-MYC axis. [Extracted from the article]