Reports Summarize Pharmaceutics Study Results from College of Pharmacy (Customizable Self-Microemulsifying Rectal Suppositories by Semisolid Extrusion 3D Printing).

Researchers at the College of Pharmacy have developed a customizable self-microemulsifying drug delivery system (SMEDDS) suppository for ibuprofen using semisolid extrusion 3D printing technology. The optimal formulation consisted of 10% Triacetin, 80% Gelucire 48/16, and 10% Tetraethylene glycol, which showed improved drug absorption in the rectum. The study suggests that SMEDDS-3DPS can enhance the rectal bioavailability of ibuprofen and highlights the versatility of 3D printing in manufacturing lipid-based suppositories tailored to individual patient needs. [Extracted from the article]