Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation (Updated October 10, 2024).

The article discusses the role of Leiomodin 1 (LMOD1) in myogenic differentiation, a process crucial for muscle regeneration. Through mass spectrometry, researchers identified LMOD1 as a key regulator that influences the formation of myotubes. The study suggests that LMOD1 interacts with the deacetylase SIRT1, impacting the expression of target genes essential for myogenic differentiation. This research may offer insights into improving muscle regeneration in aging and disease conditions. [Extracted from the article]