Biosynthesis of glucosaminyl phosphatidylglycerol in Pseudomonas aeruginosa.

The article discusses the biosynthesis of glucosaminyl phosphatidylglycerol (GlcN-PG) in Pseudomonas aeruginosa, a Gram-negative aerobic bacterium. Through bioinformatic and lipidomic analysis, a 3-gene operon named gpgSDF was identified as responsible for the biosynthesis and potential transport of GlcN-PG in P. aeruginosa. The study sheds light on the biological and pathological functions of GlcN-PG, which could impact our understanding of membrane physiology, pathogenesis, and antimicrobial resistance in P. aeruginosa. [Extracted from the article]