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Investigators from University Hospital Augsburg Zero in on Life Science (Whole Blood Assay With Dual Co-stimulation for Antigen- Specific Analysis of Host Immunity To Fungal and Viral Pathogens).

Source :
Health & Medicine Week; 11/1/2024, p2901-2901, 1p
Publication Year :
2024

Abstract

Researchers from University Hospital Augsburg in Germany have developed a whole blood assay with dual co-stimulation for analyzing host immunity to fungal and viral pathogens. This new method aims to improve sample processing efficiency and reduce the need for large blood volumes typically required for antigen-specific immunoassays. The protocol includes guidance for stimulation tubes preparation, blood stimulation, and downstream sample processing for flow cytometry, cytokine secretion assays, and transcriptional analyses, making T-cell monitoring more accessible for pediatric patients and small animal studies. The research provides a versatile toolbox for complex antigen-specific immune analysis in clinical and translational research settings. [Extracted from the article]

Details

Language :
English
ISSN :
15316459
Database :
Supplemental Index
Journal :
Health & Medicine Week
Publication Type :
Periodical
Accession number :
180462802