Back to Search Start Over

Studies from University of Chittagong in the Area of Heart Attack Described (Synthesis and Elucidation of Strained Galactopyronose Esters As Selective Cyclooxygenase-2 Inhibitor: a Comprehensive Computational Approach).

Source :
Pain & Central Nervous System Week; 10/21/2024, p928-928, 1p
Publication Year :
2024

Abstract

A recent study conducted at the University of Chittagong in Bangladesh focused on the synthesis of strained galactopyranose esters as selective cyclooxygenase-2 (COX-2) inhibitors. The research aimed to develop drugs that selectively target COX-2, which is involved in various pathologies such as inflammation and cancer. The study identified potential compounds that showed enhanced binding affinity to COX-2 over COX-1, potentially reducing ulcerogenic risks associated with traditional nonsteroidal anti-inflammatory drugs. The research concluded that a novel class of COX-2 inhibitors was produced through the synthesis of these esters. [Extracted from the article]

Details

Language :
English
ISSN :
15316394
Database :
Supplemental Index
Journal :
Pain & Central Nervous System Week
Publication Type :
Periodical
Accession number :
180342676