Reports Outline Alzheimer Disease Study Findings from St. Vincent's Institute of Medical Research (Crystal Structure of Alzheimer's Disease Phospholipase D3 Provides a Molecular Basis for Understanding Its Normal and Pathological Functions).

Researchers at St. Vincent's Institute of Medical Research in Fitzroy, Australia, have identified the crystal structure of the enzyme PLD3, which is implicated in Alzheimer's disease. The study found that PLD3 exhibits nuclease activity rather than phospholipase activity, shedding light on its role in the disease. The research also identified key genetic variations that may impact Alzheimer's disease. This peer-reviewed study provides valuable insights into the molecular functions of PLD3 in Alzheimer's disease. [Extracted from the article]