Findings from Medicine School Provides New Data about Lentivirus (Macrophages Overexpressing Interleukin-10 Target and Prevent Atherosclerosis: Regression of Plaque Formation and Reduction In Necrotic Core).

A recent study conducted in Beijing, China, explored the potential of using genetically modified macrophages to target and prevent atherosclerosis, a chronic inflammatory disease. The researchers engineered macrophages to overexpress interleukin-10 (IL-10), a protein known for its anti-inflammatory effects. These modified cells were then introduced into mice with atherosclerosis, resulting in a reduction in plaque formation and necrotic core. The study suggests that cell therapy using anti-inflammatory macrophages could be a promising strategy for treating atherosclerosis. [Extracted from the article]